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      Match Document Document Title
      10458911 Method for searching candidate material for anti-cancer drug using localized surface plasmon resonance  
      A method for screening an anticancer candidate is disclosed. The method includes immobilizing gold nanoparticles onto a substrate; binding a protein involved in carcinogenesis and metastasis to...
      10458895 Predicting response to pemetrexed chemotherapy in non-small cell lung cancer (NSCLC) with baseline computed tomography (CT) shape and texture features  
      Methods, apparatus, and other embodiments predict response to pemetrexed based chemotherapy. One example apparatus includes an image acquisition circuit that acquires a radiological image of a...
      10457993 Biomarker RNF6 for colorectal cancer  
      The present invention provides a method for diagnosing of colorectal cancer in a subject and a method for determining risk of recurrence of colorectal cancer among colorectal cancer patients by...
      10457992 Hypermethylation biomarkers associated with poor survival outcomes for head and neck squamous cell cancer  
      In accordance with one or more embodiments, the inventors have conducted the first comprehensive integrated genomic and epigenomic analysis in HNSCC, focusing on identifying genes that have...
      10457947 Targeting of human glucocorticoid receptor beta in cancer  
      A peptide nucleic acid (PNA) referred to herein as Sweet-P, compositions comprising the methods of making the same, mid methods of using the same, are described.
      10457946 Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer  
      The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential...
      10457943 Antisense oligonucleotides for treatment of cancer stem cells  
      The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing...
      10457938 TTV miRNA sequences as an early marker for the future development of cancer and as a target for cancer treatment and prevention  
      Described are TTV miRNAs and probes and primers comprising part of said TTV miRNA polynucleic acid. The use of said compounds for diagnosis of cancer or predisposition of cancer is also described.
      10457740 Methods and compositions for treating cancer using P2RX2 inhibitors  
      The present invention provides methods for treating cancer using P2RX2 inhibitors, such as P2RX2 inhibitory antibodies, among others. The invention also features compositions containing P2RX2...
      10457734 IGF-1R antibody and its use for the diagnosis of cancer  
      The present disclosure relates to a novel antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences coding for said antibody.
      10457729 Compositions and methods for treating cancer  
      The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα)...
      10457725 Methods of treating skin cancer by administering a PD-1 inhibitor  
      The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin cancer). The methods of the present invention comprise administering to a...
      10457718 Compounds for the treatment of cancer  
      The technology provided herein relates to novel isolated polypeptides and peptides having a growth inhibitory effect on human cancer cells. Nucleic acid molecules encoding said...
      10457679 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer  
      The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1, R2, R3, R4 and R5 have any of the meanings defined herein. The...
      10457676 Capsazepine analogs for the treatment of cancer and other proliferative diseases  
      The present disclosure relates generally to derivatives of capsazepine and methods of use thereof In some aspects, the present disclosure relates to using capsazepine derivatives to treat cancer...
      10457662 Substituted amides for treating and preventing cancer  
      This invention is in the field of medicinal chemistry. In particular, the invention relates to novel small molecule compounds having a quinolin-8-yl-nicotinamide structure (e.g., a compound having...
      10457642 211-astatine containing radiotherapeutics for the treatment of cancer  
      Described herein is an alpha-emitting radionuclide, 211At, which has been incorporated into a selective sigma-2 ligand moiety to provide cytotoxic capabilities to a chemical compound. As described...
      10457639 Fluorescent regulators of RASSF1A expression and human cancer cell proliferation  
      The invention provides methods for the treatment of cancer in a subject comprising administering a dansyl-carbazole compound.
      10456469 Glutamine-high Z element compounds for treating cancer  
      The present invention is a glutamine compound having a non-radioisotope high Z element attached via a linker, which enters the mitochondrion and is subsequently exposed to ionizing radiation. When...
      10456420 Genetically modified NK-92 cells and monoclonal antibodies for the treatment of cancer  
      This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.
      10456407 Combination therapy for treating cancer  
      The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents (such as tyrosine kinase inhibitors or...
      10456399 Method for treating cancer patients with severe renal impairment  
      A method for treating cancer in patients with creatinine clearance of 15 mL/min or more and less than 30 mL/min, including dividing a combination drug containing α,α,α-trifluorothymidine (FTD) and...
      10456388 Antihistamine for use in treatment of breast cancer  
      Disclosed herein is desloratadine or ebastin for use in treatment of a patient diagnosed with breast cancer. Also disclosed is desloratadine or ebastin for use in treatment of a patient diagnosed...
      D864395 Cover for cancer cell observation camera  
      10452970 Methods and systems of evaluating a risk of a gastrointestinal cancer  
      A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target...
      10451626 Method for detecting a solid tumor cancer  
      A method for indicating a presence or non-presence of a predefined solid tumor cancer in an individual, comprising the steps of: A. Providing at least one biological sample originating from said...
      10451625 Methods of detecting cancer  
      Method and kits for detecting cancer, and in particular breast cancer, in a subject by measuring the levels of at least one of a series of biomarkers, as compared to a control sample lacking...
      10450357 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
      The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
      10450289 Substituted β-lapachones for treating cancer  
      Provided herein are compounds having the general formula compositions, and methods useful for treating cancer and neurodegeneration. The compounds comprise a mitochondria-targeting moiety linked...
      10450281 Compounds and methods for treating cancer  
      Provided are small molecule inhibitors of ubiquitin specific protease 2, 8 and 12 (USP2 and USP8 and USP12) activity and methods for their use in treating cancers. The small molecule inhibitors of...
      10450278 Substituted 2-thioxo-imidazolidin-4-ones and spiro analogues thereof, active anticancer ingredient, pharmaceutical composition, medicinal preparation, method for treating prostate cancer  
      Novel (R)-stereoisomers of substituted 2-thioxo-imidazolidin-4-ones of formula 1, or spiro analogues thereof, which exhibit androgen receptor antagonist properties. Also provided are variants of a...
      10450275 Compounds and methods for treating cancer, neurological disorders, ethanol withdrawal, anxiety, depression, and neuropathic pain  
      Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
      10449239 Peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers  
      The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
      10449238 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
      The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
      10449202 Rationale-based design of a targeted therapy for cancer  
      The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are...
      10449200 Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer  
      Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous recombination in the tumor cells, and...
      10449197 Systems and methods for treating cancer  
      Embodiments of the invention provide a method of treating cancer, the method comprising providing a subject having cancer cells, and contacting the cancer cells with a therapeutically effective...
      10449191 Treatment of prostate cancer  
      Methods for treating prostate cancer, including advanced prostate cancer, in a subject in need thereof, include administering once-daily to the subject, at least 80 mg of...
      10449186 Phenylethynyl-substituted benzenes and heterocycles for the treatment of cancer  
      Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that...
      10449178 Glucocorticoid receptor modulators to treat pancreatic cancer  
      Methods and compositions for treating a subject hosting a non-ACTH-secreting pancreatic tumor are disclosed. The methods include administering to the subject a chemotherapeutic agent and a...
      10449144 WT1 peptide cancer vaccine composition for transdermal administration  
      The present invention provides a cancer vaccine composition for transdermal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a...
      10448989 High-frequency electroporation for cancer therapy  
      The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative...
      10448637 Inhibitors of GRB2-associated binding protein 1 (GAB1) and methods of treating cancer using the same  
      Identification and evaluation of a set of first-in-class potent inhibitors targeting a new cancer target, Grb2-associated binder?1 (GAB1), which integrates signals from different signaling...
      10445619 Automatic glandular and tubule detection in histological grading of breast cancer  
      Methods, systems, and apparatuses for automatically identifying glandular regions and tubule regions in a breast tissue sample are provided. An image of breast tissue is analyzed to detect nuclei...
      10444238 Detection of ovarian cancer using antibody arrays  
      Disclosed are antibody arrays for the detection of cancer in a human or animal subject, comprising a solid support having disposed thereon in a predetermined spatial configuration, a panel of...
      10444237 Anti-pancreatic cancer monoclonal antibody and use thereof  
      A hybridoma cell line NM002-1 secreting an anti-human pancreatic cancer monoclonal antibody and deposited under CCTCC Accession NO: C201173. Also, an anti-human pancreatic cancer monoclonal...
      10444235 Systems and methods for treating, diagnosing and predicting the response to therapy of breast cancer  
      This present invention systems and methods of accessing/monitoring the responsiveness of a breast cancer to a therapeutic compound.
      10443105 Methods and compositions for correlating genetic markers with prostate cancer risk  
      The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and...
      10443104 Breast cancer susceptibility gene GT198 and uses thereof  
      It has been discovered that the human GT198 gene (gene symbol PSMC3IP) at chromosome 17q21 acts as a tumor suppressor. The mutation of the GT198 gene causes the increased dominant negative splice...
      10443102 Recurrent SPOP mutations in prostate cancer  
      The invention relates generally to new prostate cancer markers, and particularly to a class of cancer marked by the presence of missense mutations in SPOP, an E3 ubiquitin ligase component. The...

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